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that 50x4 alpine amp should do fine for the front and rear speakers.
I'd do as you say and run less power to the rears.
I'd also just go with Quart 4x6s as well. keep them all timbre matched that way.

I have a set of MB Quart RCE-216 components for my '02 Silverado Ext. cab. Here are the specs:

6.5" 2-way component / coaxial system with .75" tweeter Key Features :

Impedance: 4 Ohms
Frequency Response: 40-32k
Sensitivity: 90dB
Power Range: 60-130 watts
Crossover Freq: 4200 Hz
Crossover Slope: 12 dB/octave
Components: 2) RTE20 Titanium Tweeter .8" (19mm)
2) RWE160 Midrange 6.5" (160mm) REFERNCE Midrange Driver
2) RXE216 Crossover for Refernce Series Systems
2) Phaseplug for coaxial install

I thought about the Alpine MRP-F450 but was told it was an okay amp. What would be best for these speakers? I am also replacing my 4 x 6 speakers in the rear doors. What should I get for 4 x 6s and should I power all the speakers and then turn down the power to the 4 x 6s and keep more power to the components?

Thanks!